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U.S. Department of Health and Human Services Office of Disease Prevention and Health Promotion

Use of a 2-Dose Schedule for Human Papillomavirus Vaccination — Updated Recommendations of the Advisory Committee on Immunization Practices

About this resource:

Non-Systematic Review

Source: Centers for Disease Control and Prevention

Last Reviewed: August 2017

Workgroups: Immunization and Infectious Diseases Workgroup

This report updates previous Advisory Committee on Immunization Practices’ (ACIP) recommendations for human papillomavirus (HPV) vaccination to include a 2-dose schedule for children and adolescents who start the vaccination series before age 15 years. 

ACIP recommends the following schedule for routine HPV vaccination:

  • For people starting the vaccination series before their 15th birthday: 2 doses of HPV vaccine, given  6 to 12 months apart
  • For people starting the vaccination series after their 15th birthday: 3 doses of HPV vaccine, with the second dose given 1–2 months after the first dose, and the third dose given 6 months after the first dose

ACIP also recommends the 3-dose schedule for immunocompromised people.

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Objectives related to this resource (2)

Increase the proportion of adolescents who get recommended doses of the HPV vaccine — IID‑08
Improving
Reduce infections of HPV types prevented by the vaccine in young adults — IID‑07
Baseline only

Suggested Citation

1.

Meites E, Kempe A, Markowitz LE. (2016). Use of a 2-Dose Schedule for Human Papillomavirus Vaccination — Updated Recommendations of the Advisory Committee on Immunization Practices. Retrieved from https://www.cdc.gov/mmwr/volumes/65/wr/mm6549a5.htm.